So, I wonder if anyone can give me a good explanation for this. What is the damage that is happening?
What is the mechanism behind the injury? I thought that at most you could only damage their CB receptors with spice.
What is it that causes people to die, theoretically? Are my organs damaged when I take a night flare, for example ab-fubinaca?
It is confusing to me because THC is so “kind” to the body itself .. Then the relatives should also follow the same rule I think, but obviously I am completely wrong there, It is a dose issue quite clearly – but overall you can say that some cannabinoids risk killing one in case of overdoses, yes. The greater the dose, the greater the risk that you will experience side effects that can kill.
Then, some cannabinoids are more likely to cause harm than others, depending on the specific receptors they stimulate, just as Friman1987 writes. These are chemicals we talked about here – some of them are harmful to humans. For example, T-red is dangerous even though it is “related” to alcohol. If it is so important for you to do drugs, you must get real drugs. Otherwise you will be there one day. There are chemicals in your bread / yogurt that you cook in the morning (sugar, etc.), your coffee (caffeine, etc.), the chocolate you eat (theobromine, etc.), and so on endlessly.
T-red is not “related” to alcohol, it is alcohol. Exactly the same fine ethanol as in absolute vodka or any damn alcoholic beverage, and therefore not a dew more dangerous.
On topic: It is very unexplored with synthetic cannabinoids purely in terms of research, you who are doing it have no idea what experimental rabbits you really are. Cannabis and THC, CBD, etc., there is a huge amount of research around, but how would anyone manage to research any new synthetic cannabinoids that pops up as the elderly are banned. Really insidious to keep up with.Where do the leftovers take you think? we take ab-fubinaca as an example
N – [(1S) -1- (Aminocarbonyl) -2-methylpropyl] -1 – [(4-fluorophenyl) methyl] -1 H -indazole-3-carboxamide
Although the synthesis turns on the CB2 receptors, they must get there first. then the body wants to clear out the “poisons” or how to describe it, which causes the body to turn upside down ..
How do you think it really works with drugs? why can we urinate on urine for drugs several days after use? Because it remains in the body!
Why people die is simple, the body does not know how to react to the synthetic chemical you have taken
The first defense mechanism the body has when you have something in you, is to vomit if you have got in too much or if the body does not want it left in it does not work, so the body tries to sweat it out and lastly pee it out
Before the body has sweated it out or tried to spew it out, the body does everything to get rid of the toxins in your body and then anything can happen, it can even do so “the brain” shuts itself off because it does not know how it should attack the chemicals which means that you do not breathe and die the body can also put you in a long-term coma because it wants to only fight off the chemicals in your body and not have you under awake condition so it must think of you ok
these are examples. but I think you probably understand the point, as Entheogen writes, synthetic cannabinoids are largely unexplored and therefore it is not possible to say that they are so or so harmful. It can be assumed compared to THC which is also a cannabinoid that most synthetic cannabinoids are not lethal if the doses are around EC50. What I mean is that as long as you do not exceed the maximum effective dose and overdose, the effect will not render in death seen from a probability perspective.
However, these synthetic compounds are so unknown that one cannot know for sure exactly how and what in the brain they affect – or whether they damage vital organs which the dr-snuggle is in.
All in all, it is not the potency that is what one should look for – but how the metabolism occurs and what chemicals are formed during the breakdown of the substance in question. This is difficult because no adequate research is being conducted on synthetic cannabinoids. Thus, those who use them are lax subjects who report side effects rather than researchers who report the same side effects fixed in mice, rats, and the like.